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Posts sent in: May 2008

16 May 2008 
Drug and drug allergies - is secondary increased immune response to specific drugs or their components, accompanied by general or local clinical manifestations.
Drug allergies can occur as a complication in the treatment of a disease or as occupational disease due to prolonged exposure to drugs and medicines (from doctors, health workers, pharmacists). According to statistics, among the urban population drug allergy occurs more frequently among women aged 31-40 years. The main causes of development of allergies to medicines:
-- Hereditary, caused by genetically predisposed;
-- Availability of other types of allergies (bacteria, pollen, food, etc.);
-- Prolonged use of sick (in healthy - contact) drugs, especially repeated courses;
-- Use of depot preparations (for example, bitsillin);
-- The simultaneous appointment of a large number of drugs from different groups (poliprogmaziya), products of metabolism which may reinforce each other allergens effect;
-- Physical-chemical structure, high sensibiliziruyuschaya drug activity.
Allergic reaction to medication may arise from drugs overdose (in this case it was a reaction psevdoallergicheskoy).
Virtually all drugs can trigger allergic reactions. In most cases, cause allergic reactions are antibiotics, local anaesthetics, non-steroid anti-drugs, etc. One appeared, drug allergy will arise again and again when re-admission of drugs.
It must be remembered that opportunities for development of allergic reaction is needed sensebilizatsii period, the duration of which differs from the various allergens and reactivity depends on the organism. On average, this period is 7-10 days. Immediately allergic reactions to drugs developed from several seconds to several hours and could provoke severe reactions such as anafilaktichesky shock, bronchial asthma attack, rash, edema Kvinke, as well as conjunctivitis and allergies, etc. One of the worst manifestations of drug allergies - anafilaktichesky shock, expressed sharp decline in blood pressure - is a life-threatening condition and requires immediate assistance.
Clinical forms (for containment and engagement of organs and systems)
Generalized:
-- Anafilaktichesky shock;
-- Serum sickness and syvorotochnopodobny syndrome (STI-visceral form of drug allergies);
-- Fever;
-- Generalized vaskulity in combination with other diseases.
Localized (organ and system):
-- Skin lesions;
-- Toksikodermii defeat internal organs (Layella syndrome, Stevens-Johnson);
-- Hematologic destruction;
-- Vaskulity;
-- Visceral (internal organs);
-- Mucous membranes and respiratory system;
-- Nervous system.
To identify the causes of drug allergies need to undertake a survey. To determine patient portability of certain medicines, used different diagnostic tests, after which the doctor-patient allergology gives recommendations on the possibility of receiving those or other medicines.
For prevention of drug allergies should observe the following rules:
-- Remember, but better - to save the name of the drug, causing allergic manifestations;
-- Warn health workers on the reactions to those or other drugs;
-- Before stranger to take medication, consult with a physician.
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Admin · 11027 views · 2 comments
16 May 2008 
For pregnant women is helpful chocolate, as it positively affect the performance of the cardiovascular system. Such a statement made by scientists at Yale University of Connecticut, analyze its properties are among more than two thousand mothers.

Women are not harmful pampered themselves during pregnancy chocolate - this product helps prevent serious complications of childbirth. Chocolate, particularly dark, rich feature called zeobromin (theobromine), which encourages the work of the heart, relaxes muscles, increases blood vessels, reduces pain in the chest, strengthens the arteries and reduces the pressure.

It was found that women who during the first and third trimester of pregnancy consumed five or more tiles of chocolate every week, had the highest concentration zeobromina in the body and by 69% reduced risk of complications during and after childbirth. According to the doctors, zeobromin also improves blood circulation in the placenta.

However, it must be remembered that in the opinion of doctors frequent use of chocolate in women during and after pregnancy (pregnancy if the child is breastfed) may lead to the child's allergy.
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Admin · 11288 views · 1 comment
16 May 2008 
Even someone who has been living under a rock for the last five or so years would be aware of the confusion, misconception and questions that exist regarding generic prescription drugs, especially the largest selling online, by far, Viagra (Sildenafil Citrate) and other drugs used for the treatment of erectile dysfunction.

Some people believe much of the misinformation published by those who would have them pay ten times more for genuine drugs rather than the far cheaper generic versions. Much of the confusion and misconception exists because, understandably, many can’t see how the generic drug can be the same thing but be so cheap. Well, here is why the vast difference exists. It’s no secret, nor is it difficult to understand. It’s simply economics versus opportunism (although sometimes justified).

The following applies to all generic drugs sold through online pharmacies and in retail pharmacies on the street. There is no difference.

When the drug is first researched, discovered and developed, it takes a number of years and many, many millions (if not billions) of dollars in research, failure, more research, testing through multiple stages. Then come the trials, which have to satisfy the likes of the FDA (most countries have their own version of the FDA), which can, again, take years and more millions and even still fail for one reason or another.

Once the drug is approved by the authorities as safe (or relatively so, with the appropriate warnings…), the drug company then have to spend more millions and months marketing and promoting it to the public and the medical profession and wait for them to become confident in the product. Then comes the mass manufacture, packaging, wholesaling, and distribution etc of the tablets or whatever form the drug tales.

Interestingly, for instance, from the time the patent was taken out on Viagra in 1993 it took five years, till 1998, before it could be sold. Huge investments in money, time and resources, which the drug company (and shareholders) needed desperately to recover, hopefully in short order. Who can blame them, really? It’s a huge investment and huge risk with any new drug and some don’t end up being worthwhile.

That’s why any original drug is relatively expensive compared to it's generic counterpart. At least for the first decade or so, while these enormous investments are being recovered. Very simple indeed.

Now for generic drugs, of which there are many. First of all, they are generally manufactured overseas because of cheaper labor and production costs and also because the patent doesn’t allow for them to be made or sold in the U.S. (if that's where they were originally discovered and patented) except by the patent owner. They can however, be imported, in personal quantities by individuals, in most countries.

Before we go any further, as I said, many other countries have their own versions of the FDA, which are every bit as stringent and effective. Those countries that don’t have such an authority rely on the World Health Organization (W.H.O.) to approve and monitor the manufacture of already proven pharmaceuticals. Let’s face it, when people get sick in Australia, Britain, India, Russia, China, Japan etc and take the drugs made in their own country, they get better. The U.S is NOT the only place in the world that can be trusted to make quality, safe and effective pharmaceuticals. It would be silly and cynical to think so.

In fact, it may surprise some that the bulk ingredients for some so-called 'US manufactured' drugs are actually imported from other countries, so let’s be realistic!

The Generic drug that is purchased online is GENERALLY made in pharmaceutical facilities, which are approved by authorities much the same as the FDA and/or W.H.O. It is also interesting to note that vast amounts of GENERIC drugs like antibiotics, immunizations, birth control pills and even Viagra are used by the likes of W.H.O., World Vision and the Red Cross etc in their humanitarian endeavors because of their vastly cheaper prices. If they're good enough for The Red Cross, are they good enough for you? I think so...

Generic Drugs that are sold through Online Pharmacies are so cheap because of the cheaper labor in other countries, but more so because of the obvious following reasons:

NO huge initial investment to recover.
NO wholesalers, distributors or retailers, they are shipped to the client from the manufacturer.
NO transport costs between three, four or often five of the above organizations.
NO stock needs to be kept by any of these non-existent middlemen or Pharmacies.
NO ‘bricks and mortar’ premises need to be maintained by the middlemen or the Pharmacies.

So you see, the ongoing mark-ups or profits from each of these middlemen don’t exist because they don’t exist, just the price from the manufacturer and their commission to the referring Online Pharmacy.

In closing, I must admit that there ARE counterfeit drugs and there are drugs, which don’t contain much of the effective ingredient. This problem is seen more so in drugs like Viagra, cialis and Levitra (the ED drugs) because of their popularity but STILL, these account for a very small percentage indeed, of the quality generic drugs sold online. People are still buying online drugs in droves and they wouldn’t continue to do that if they were having bad or questionable experiences, would they?

It’s also been discovered that the counterfeit drugs that everyone seems to condemn online Pharmacies over, ALSO show up in ‘bricks and mortar’ Pharmacies. So, why aren’t people wary of these retail outlets? Easy… media and the original manufacturer’s hype. Of course they’d rather sell all the online buyers genuine drugs at a much higher rate.

As for the best way to tell a safe online Pharmacy, look for a toll free phone number and other means of contact, for following up orders, requesting cancellations, refunds or complaints. If they have these, they can hardly be surviving by selling inferior products. Check out the contacts first if you wish to make sure they’re genuine.

This article is written in the spirit of assisting those who have a need for prescription drugs but are unable to, or have difficulty in, financing their urgent needs. Generic drugs are safe, in the main and online pharmacies are honest and helpful, also in the main. Action is continually being taken against pharmacies (both online and on the street), which sell inferior products. Hopefully we will soon have worldwide pharmacy access, which all people can trust and take advantage of.


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Admin · 238 views · Leave a comment
16 May 2008 
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Admin · 83 views · 1 comment
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